Towner JS, Sealy TK, Khristova ML, Albariño CG, Conlan S, Reeder SA, et al. Newly discovered Ebola virus associated with hemorrhagic fever outbreak in Uganda. PLoS Pathog. 2008;4:e1000212. DOIPubMedGoogle Scholar
Wamala JF, Lukwago L, Malimbo M, Nguku P, Yoti Z, Musenero M, et al. Ebola hemorrhagic fever associated with novel virus strain, Uganda, 2007–2008. Emerg Infect Dis. 2010;16:1087–92. DOIPubMedGoogle Scholar
MacNeil A, Farnon EC, Wamala J, Okware S, Cannon DL, Reed Z, et al. Proportion of deaths and clinical features in Bundibugyo Ebola virus infection, Uganda. Emerg Infect Dis. 2010;16:1969–72. DOIPubMedGoogle Scholar
MacNeil A, Farnon EC, Morgan OW, Gould P, Boehmer TK, Blaney DD, et al. Filovirus outbreak detection and surveillance: lessons from Bundibugyo. J Infect Dis. 2011;204(Suppl 3):S761–7. DOIPubMedGoogle Scholar
Kratz T, Roddy P, Tshomba Oloma A, Jeffs B, Pou Ciruelo D, de la Rosa O, et al. Ebola virus disease outbreak in Isiro, Democratic Republic of the Congo, 2012: signs and symptoms, management and outcomes. PLoS One. 2015;10:e0129333. DOIPubMedGoogle Scholar
Jacob ST, Crozier I, Fischer WA II, Hewlett A, Kraft CS, Vega MA, et al. Ebola virus disease. Nat Rev Dis Primers. 2020;6:13. DOIPubMedGoogle Scholar
Feldmann H, Sprecher A, Geisbert TW. Ebola. N Engl J Med. 2020;382:1832–42. DOIPubMedGoogle Scholar
Africa Centres for Disease Control and Prevention. Bundibugyo virus disease fact sheet. Addis Ababa: The Centres; 2026 [cited 2026 Jul 13]. https://khub.africacdc.org/records/resource/bundibugyo-virus-disease-fact-sheet
Lhomme E, Wiedemann A, Ayouba A, Ben-Farhat S, Thaurignac G, Roy C, et al.; PREVAC Study Team. Cross-reactive Bundibugyo antibody responses after receipt of licensed Ebola vaccines. N Engl J Med. 2026;395:612–5. DOIPubMedGoogle Scholar
World Health Organization. WHO Technical Advisory Group on candidate vaccine prioritization: meeting report, 19 and 25 May 2026. Geneva: The Organization; 2026.
World Health Organization. WHO Technical Advisory Group on Therapeutics Prioritization for Bundibugyo virus disease: meeting report, 20 and 26 May 2026. Geneva: The Organization; 2026.
Zomahoun DL, Boyd MA, Honein MA, Montgomery JM, Zielinski-Gutierrez E, Meites E, et al. CDC 2026 Ebola Response. Notes from the field: outbreak of Ebola disease caused by Bundibugyo virus—Democratic Republic of the Congo and Uganda, May 2026. MMWR Morb Mortal Wkly Rep. 2026;75:293–4. DOIPubMedGoogle Scholar
Uganda Ministry of Health. Ebola Bundibugyo virus disease outbreak 2026. Kampala: The Ministry; 2026 [cited 2026 Jul 13]. https://evd-daily.health.go.ug
World Health Organization. Disease outbreak news: epidemic of Ebola disease in the Democratic Republic of the Congo and Uganda determined a Public Health Emergency of International Concern. Geneva: The Organization; 2026 May 17 [cited 2026 Jul 13]. https://www.who.int/emergencies/disease-outbreak-news
Africa Centres for Disease Control and Prevention. Africa CDC declares the ongoing Bundibugyo Ebola outbreak a Public Health Emergency of Continental Security. Addis Ababa: The Centres; 2026 May 18 [cited 2026 Jul 13]. https://africacdc.org/news-item/africa-cdc-declares-the-ongoing-bundibugyo-ebola-outbreak-a-public-health-emergency-of-continental-security
Frieden TR, Lee CT, Bochner AF, Buissonnière M, McClelland A. 7-1-7: an organising principle, target, and accountability metric to make the world safer from pandemics. Lancet. 2021;398:638–40. DOIPubMedGoogle Scholar
Resolve to Save Lives. The 7-1-7 target: early disease detection & outbreak response. New York: Resolve to Save Lives; 2026 [cited 2026 Jul 13]. https://resolvetosavelives.org/how-we-save-lives/epidemic-prevention/7-1-7
Bochner AF, Makumbi I, Aderinola O, Abayneh A, Jetoh R, Yemanaberhan RL, et al. Implementation of the 7-1-7 target for detection, notification, and response to public health threats in five countries: a retrospective, observational study. Lancet Glob Health. 2023;11:e871–9. DOIPubMedGoogle Scholar
Jean Louis F, Nichols L, de la Torre C, Dahourou AG. Strengthening outbreak detection in Africa to achieve the 7-1-7 global framework: challenges and opportunities. Public Health Rev (Minneap). 2025;46:1608039. DOIPubMedGoogle Scholar
Nakiire L, Bochner AF, Nabatanzi M, Kisakye AK, Kayiwa J, Lee C, et al. Implementing the 7-1-7 target to improve epidemic preparedness and response in Uganda. BMJ Glob Health. 2025;10:e018207. DOIPubMedGoogle Scholar
Katumba H, Migisha R, Mutesi C, Ainembabazi B, Naiga HN, Namakula LO, et al. Application of the 7-1-7 framework in a prototypical anthrax outbreak: identifying missed opportunities for early detection in southwestern Uganda, September 2024. IJID One Health. 2026;12:100136. DOIGoogle Scholar
World Health Organization. Guidance and tools for conducting an Early Action Review (EAR): rapid performance improvement for outbreak detection and response. Report no. WHO/WPE/HSP/CER/2023.1. Geneva: The Organization; 2023.
World Health Organization. International health regulations (2005). 3rd edition. Geneva: The Organization; 2016.
Akilimali P, Ebengo DM, Scarpino SV, Amuri-Aziza A, Wawina-Bokalanga T, Matondo-Mbundu P, et al. Clinical characteristics of patients infected with Bundibugyo virus, DRC, 2026. N Engl J Med. 2026;395:610–2. DOIPubMedGoogle Scholar
Eleeza O, Barrera-Cancedda AE, Mutebi RR, Njenga A, Vandi MA, Mearns S, et al. Epidemic-ready primary healthcare and the application of 7-1-7 metrics: a case study on a measles outbreak in Sierra Leone, January to March 2024. Health Secur. 2025;23:369–75. DOIPubMedGoogle Scholar
Sullivan NJ. Bundibugyo virus disease in 2026—clinical and public health responses. N Engl J Med. 2026;395:278–89. DOIPubMedGoogle Scholar
Fekadu ST, Gebrewahid AL, Mankoula W, Eteng W, Lokossou V, Kawe Y, et al. Public health emergency operations centres in Africa: a cross-sectional study assessing the implementation status of core components and areas for improvement, December 2021. BMJ Open. 2023;13:e068934. DOIPubMedGoogle Scholar
Mayigane LN, Vedrasco L, Chungong S. 7-1-7: the promise of tangible results through agility and accountability. Lancet Glob Health. 2023;11:e805–6. DOIPubMedGoogle Scholar
Agbo S, Gbaguidi L, Biliyar C, Sylla S, Fahnbulleh M, Dogba J, et al. Establishing national multisectoral coordination and collaboration mechanisms to prevent, detect, and respond to public health threats in Guinea, Liberia, and Sierra Leone 2016–2018. One Health Outlook. 2019;1:4. DOIPubMedGoogle Scholar
