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Watch: Alix Earle and Ashtin Earle Test Positive for

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Alix Earle Details Emotional Experience Getting BRCA Results on Camera

Watch: Alix Earle and Ashtin Earle Test Positive for BRCA2 After Mom’s Cancer Diagnosis

Alix Earle is speaking out about her health journey.     

After she and her younger sister Ashtin Earle both tested positive for the BRCA2 gene mutation—which was documented on Netflix’s Earle Meets World—she detailed the experience of learning she had an increased cancer risk while cameras were rolling. 

“It was hard,” Alix exclusively told E! News’ Erin Lim Rhodes at the Earle Meets World premiere Sept. 1. “Even the moments where I’m like, ‘I just want to go [be] alone and cry right now.’”

“When we were going through it, though, I didn’t really think much about the cameras,” she continued, “because we were so focused on each other and just being there and supporting each other.”

While it wasn’t easy, the 25-year-old—who shared her mom Alisa Maniaci’s breast cancer diagnosis in January—doesn’t regret giving the world an inside look at such an emotional moment.

“It’s a really powerful story,” she explained, “and I’m happy that we captured it.”

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Alix Earle Calls Out Her Family for Being “Team Braxton” In Explosive Earle Meets World Trailer

“It’s unfortunate when things happen in life that aren’t the best, especially with health, but we had cameras up for all of this,” Alix continued. “And that’s sort of the whole show, we just kept everything going as things were naturally happening in our lives.”

As she put it, “These few months happened to just be a wild ride. But I’m really excited for it to be out there.”

Indeed, Earle Meets World—streaming now on Netflix—gives fans a behind-the-scenes look at Alix’s family dynamic for the first time, including showing the moment Alix and Ashtin, 23, were told they both tested positive for the BRCA2 gene after deciding to take the test following their mom’s diagnosis.

While the trio became emotional after genetic counselor Pankti Doshi revealed the results, Alix expressed that she was grateful that she and her sister got answers—and more importantly, have their family to lean on for support.

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“At least we’re in it together, and at least we know,” Alix told Ashtin. “And it’s such a privilege to be able to know and to have each other’s back.”

Alisa—who shares the girls with ex-husband Thomas “TJ” Earle—agreed with her daughter’s sentiment, assuring Alix and Ashtin, “Nothing’s happening to either of you, nor me. Listen, we’re all gonna be strong. We’re all gonna be fine. We all know that we can be on top of it now.”

For more celebrities who have opened up about their own cancer journeys, keep reading…

Colin EgglesfieldThe All My Children alum announced in January 2025 that he had been diagnosed with prostate cancer, his third cancer diagnosis throughout his life.Despite the devastating news, he announced (for the third time) in February 2025 he was cancer-free following successful surgery and treatments.“Remember, you’re not defined by any of your challenges,” he wrote in his February 2025 Instagram update. “You’re grander than it all. I’m not my fear, my anxiousness or my scars but I embrace it all because the only way to transform it is to own it.”
Gerry TurnerThe former Golden Bachelor star shared in Dec. 2024 that he had been diagnosed with Waldenström’s macroglobulinemia, a bone cancer.”Unfortunately, there’s no cure for it,” Gerry noted to People at the time. “So that weighs heavily in every decision I make. It was like 10 tons of concrete were just dropped on me. And I was a bit in denial for a while, I didn’t want to admit to it.”
Ariana Madix”I had to have a lil bit o’cancer removed from my body and lymph nodes biopsied,” the Vanderpump Rules star revealed to fans at the close of 2018. “(In the clear now!)”
Christina ApplegateThe Up All Night star was declared “100-percent clear” of breast cancer after treatment and a double mastectomy.
Jim BeaverThe actor, known for roles in The Boys and Supernatural, shared on Feb. 3, 2023, that he had battled prostate cancer for years and was cancer free.
Marcia CrossThe Desperate Housewives star revealed to fans in September 2018 that she survived anal cancer. “After posting a picture of myself here and uttering the words #cancer and #hairloss, I feel liberated, deliriously free and completely me,” she shared on Instagram
Dustin HoffmanThe two-time Oscar winner underwent successful treatment for cancer, and his rep confirmed to E! News that doctors deemed Hoffman “surgically cured.”
Hugh JackmanThe X-Men star was treated for his third basal cell carcinoma back in 2014, and after his third treatment, Jackman’s rep told E! News that he’s “all good” now.In April 2023, Hugh had two biopsies for additional basal cell carcinoma. At the time, he told fans, “If I can just take this opportunity to remind you summer is coming for those of us in the northern hemisphere, please wear sunscreen.”
Camille GrammerThe former Real Housewives of Beverly Hills star celebrated one year of being cancer-free in January. The mother of two was diagnosed with endometrial cancer back in 2013 and underwent a radical hysterectomy.Then in 2017, Camille had surgery to remove Squamous Cell Carcinoma, a type of skin cancer. 
Gordon RamsayAlongside a pair of photos that show a line of stitches running from the bottom of his ear to his jaw, which he later covered with a bandage, the British celebrity chef shared that he underwent a procedure to treat skin cancer.“Grateful and so appreciative for the incredible team at The Skin Associates and their fast reactive work on removing this Basal Cell Carcinoma,” Gordon wrote on Instagram August 2025. “Please don’t forget your sunscreen this weekend.”“I promise you it’s not a face lift,” he added. “I’d need a refund…”
Cobie SmuldersThe Avengers: Age of Ultron actress battled ovarian cancer at the age of 25 and overcome odds when she welcomed two children with husband Taran Killam.
Dr. Drew PinskyTV host reveals he underwent surgery for prostate cancer in July 2013 and has since been given a clean bill of health.
Brooke BurkeThe Dancing with the Stars cohost underwent successful surgery for thyroid cancer. The mother of four tweeted, “Thx for all the twitter love. I’m [home] recovering & resting.”
Angie Everhart”MY DR CALLED ME ON A SAT. MORNING TO TELL ME I AM CANCER FREE!!!!! #wootothemotherf–kinhoo,” the actress tweeted after receiving the good news.
Michael C. HallThe Dexter star used a hiatus from his hit series to slay Hodgkin’s lymphoma.
Michelle MonaghanThe Australian actress revealed in October 2011 that she had a cancerous mole removed from her calf after her hubby encouraged her to get the suspicious-looking mark checked out.
Ewan McGregorThe Scot is trainspotting just fine these days after having a cancerous mole removed from beneath his right eye.
Sheryl CrowThe singer beat breast cancer in 2004 with a “minimally invasive” lumpectomy and radiation therapy.
Michael DouglasThe Oscar winner declared in early 2011 that his tumor was gone and he had throat cancer “beat.”
Edie FalcoThe Emmy winner whacked breast cancer in 2004.
Anderson CooperSurely the CNN veteran wears his SPF when he’s braving the elements now after having a cancerous growth removed from under his left eye in 2008.
Kylie MinogueThe Australian pop star underwent successful surgery for breast cancer in 2005.
Barry WatsonThe 7th Heaven star was diagnosed with Hodgkin’s disease when he was only 28. He’s 50 now and looking good!
Maura TierneyThe ER fave had to abandon her role in Parenthood to fight breast cancer in 2009—but her treatment was a success and she was back on the red carpet in no time.
Sharon OsbourneThe America’s Got Talent judge was diagnosed with colon cancer while shooting The Osbournes in 2002 and used the opportunity to stress the importance of regular screenings while attacking the #@%! with chemotherapy. She was declared cancer-free the following year.
Robert De NiroThe Oscar winner took prostate cancer down, down to Chinatown, in 2003, and has been in about 400 movies since then.
Robin RobertsThe Good Morning America cohost proudly flaunted her smooth scalp while undergoing chemotherapy to treat breast cancer in 2007.
Lance ArmstrongThe champion cyclist battled back from stage-four testicular cancer before winning seven straight Tour de France titles.
Melissa EtheridgeThe Grammy and Oscar winner became an inspiring activist after a lumpectomy and chemotherapy cleared her of breast cancer in 2005.
Julia SweeneyThe former Saturday Night Live standout mined her breast cancer battle for comedic material that turned into God Said Ha!, her successful one-woman show that eventually went to Broadway.

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